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FITC标记的细胞表面受体PILRβ抗体

¥2980
LMAI Bio
中国/美国/欧洲
2022-03-24 19:54

上海联迈生物工程有限公司

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产品属性
供应商 上海联迈生物工程有限公司
数量 大量
靶点 详见说明书
级别 1
目录编号 LM-2690R-FITC
克隆性 多克隆
抗原来源 Rabbit
保质期 1年
抗体英文名 Anti-PILRB/FITC
抗体名 Anti-PILRB/FITC
标记物 FITC标记
宿主 Human
适应物种 Human
免疫原 详见说明书
亚型 IGg
形态 粉末、液体、冻干粉
应用范围 IF=1:50-200
浓度 1mg/ml
保存条件 -20 °C
规格 100ul
产品说明
FITC标记的细胞表面受体PILRβ抗体
英文名称 Anti-PILRB/FITC
中文名称 FITC标记的细胞表面受体PILRβ抗体
别    名 PILRB; Paired immunoglobulin-like type 2 receptor beta; Activating receptor PILR beta; Cell surface receptor FDFACT; Cell surface receptor FDFACT1; Cell surface receptor FDFACT2; FDFACT; FDFACT1; FDFACT2; Paired immunoglobulin like receptor beta; Paired immunoglobulin like type 2 receptor beta; Paired immunoglobulin like type 2 receptor beta precursor;   
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
研究领域 免疫学  信号转导  干细胞  细胞膜受体  细胞表面分子  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, 
产品应用 IF=1:50-200  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 23kDa
细胞定位 细胞膜 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PILR beta
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
Control of cell signaling via SHP-1 is thought to occur through a balance between PILRalpha-mediated inhibition and PILRbeta-mediated activation. These paired immunoglobulin-like receptor genes are located in a tandem head-to-tail orientation on chromosome 7. PILRB is the non-ITIM-bearing member of the receptor pair, which has a truncated cytoplasmic tail relative to its ITIM-bearing partner and functions in the activating role. There are three named isoforms produced by alternative splicing.

Function:
Paired receptors consist of highly related activating and inhibitory receptors and are widely involved in the regulation of the immune system. PILRB is thought to act as a cellular signaling activating receptor that associates with ITAM-bearing adapter molecules on the cell surface.

Subcellular Location:
Membrane; Single-pass type I membrane protein (Potential).

Similarity:
Contains 1 Ig-like V-type (immunoglobulin-like) domain.

Database links:

Entrez Gene: 29990 Human

Omim: 605342 Human

SwissProt: Q9UKJ0 Human

Unigene: 632314 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

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