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Nesvacumab

品牌：MedChemExpress (MCE)

Drug_Names：Nesvacumab

Catalog_No：HY-P99036

CAS：1296818-77-3

产品活性：Nesvacumab 是一种全人源的免疫球蛋白 G1 (IgG1) 单克隆抗体，能以高亲和力特异性结合并灭活 Tie2 受体配体 Angiopoietin-2 (Ang2)，但不与 Ang1 结合^[1]。

存储条件：Please store the product under the recommended conditions in the Certificate of Analysis.

热销产品：TRAC, Human (P.pastoris, His)  | CBR1, Human (P.pastoris, His)  | MUSK, Human (P.pastoris, His)  | Cardiac phospholamban/PLN, Human (P.pastoris, GST)  | Reelin/RELN, Human (P.pastoris, His)  | Outer membrane F/OmpF, E.coli (His, myc)  | Cathepsin W/CTSW, Mouse (His, myc)  | Outer membrane C/OmpC, Klebsiella pneumoniae (His, myc)  | Prolactin, Pig (His-SUMO)  | HLA-A, Human (His)  | Clumping factor B, S. aureus (His)  | Vitamin D-binding/GC, Mouse (His)  | Group XV phospholipase A2/Pla2g15, Mouse (His, myc)   | Inhibin alpha chain/INHA, Bovine (His-SUMO)  | DNA helicase II/uvrD, E.coli  | CDK5, Human (P.pastoris, His)  | Atrial natriuretic peptide receptor 2/NPR2, Human (His)  | GBA/Glucosylceramidase, Mouse (P.pastoris, His)  | Neurofilament light polypeptide/NEFL, Mouse (His)  | Histone H3, Human  | 

热门产品线：重组蛋白  |  化合物库  |  天然产物  |  荧光染料  |  PROTAC  |  同位素标记物  |  寡核苷酸

Trending products：Recombinant Proteins  |  Bioactive Screening Libraries  |  Natural Products  |  Fluorescent Dye  |  PROTAC  |  Isotope-Labeled Compounds  |  Oligonucleotides

参考文献：

Kyriakos P Papadopoulos, et al. A Phase I First-in-Human Study of Nesvacumab (REGN910), a Fully Human Anti-Angiopoietin-2 (Ang2) Monoclonal Antibody, in Patients with Advanced Solid Tumors. Clin Cancer Res. 2016 Mar 15;22(6):1348-55.