Aliertib (MLN 8237) is an orally active and selective Aurora A kinase inhibitor (ic50=1.2 nm), which binds to Aurora A kinase, resulting in mitotic spindle abnormalities \ mitotic accumulation Conclusion: aliertib (MLN 8237) can induce apoptosis and autophagy in leukemia cells by targeting the akt/mtor/ampk/p38 pathway. It has antitumor activity
Storage Condition:Powder
-20°C
3 years
4°C
2 years
In solvent
-80°C
6 months
-20°C
1 month
Signal Word:Warning
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