1. chem960
  2. 458-37-7
Curcumin | 458-37-7

Product name:Curcumin

CAS No:458-37-7
MF:C21H20O6
MW:368.3799
MDL:MFCD00008365
CID:37541
PubChem ID:24892408
Introduction

curcumin(Curcumin)Also known as curcumin\Acid yellow,It is from the ginger plant turmeric\Rhizoma Curcumae\mustard\Curry\A natural phenolic antiOxidizing agent,The main chain is unsaturated aliphatic and aromatic groups,It is a rare pigment with diketones in the plant kingdom,It belongs to diketone compounds,It is a common seasoning and food pigment,non-toxic,Choleretic\Anti infection\Make the uterus produce paroxysmal contraction\Lower bloodcholesterol\antiviral\Antibacterial\antioxidant(Stronger than α- tocopherol)\Anticoagulant \Many pharmacological effects such as lowering blood lipids and anti atherosclerosis.In recent years,Production of curcumin on various tumor cells\proliferation\The inhibitory mechanism of metastasis was found.Curcumin is highly toxic to various toxic substances such as carbon tetrachloride in vivo and in vitro\AflatoxinB1\Acetaminophen\cyclophosphamideAll have protective effects against induced liver damage,Significantly reduce alcoholic liver damage(ALI)Alkaline phosphatase in animals\r-Glutamyl transpeptidase(r-GT)activity,Prevention of experimental fatty liver.

Names and Identifiers
  • Curcumin
  • TURMERIC EXTRACT
  • 1,6-Heptadiene-3,5-dione,1,7-bis(4-hydroxy-3-methoxyphenyl)-,(E,E)-
  • 5-dione,1,7-bis(4-hydroxy-3-methoxyphenyl)-,(e,e)-6-heptadiene-3
  • 5-dione,1,7-bis(4-hydroxy-3-methoxyphenyl)-6-heptadiene-3
  • 6-Heptadiene-3,5-dione,1,7-bis(4-hydroxy-3-methoxyphenyl)-,(E,E)-1
  • curcuma
  • haidr
  • Curcumin (Synthetic)
  • Curcumin (Natural)
  • Curcumin (E 100)
  • Curcumin (technical grade)
  • CURCUMIN(AS) PrintBack
  • CURCUMIN(AS)(REQUEST QUOTE)
  • CURCUMIN(P)(Compendial Traceable) PrintBack
  • (1E,6E)-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione
  • (E,E)-1,7-bis(4-Hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione
  • 1,7-DI(4-HYDROXY-3-METHOXYPHENYL)HEPTA-1,6-DIENE-3,5-DIONE
  • C.I. 75300
  • curouma
  • diferuloylmethane
  • Diferulylmethane
  • gelbwurz
  • halad
  • Indian Saffron
  • kurkumin
  • Natural Yellow 3
  • souchet
  • Turmeric yellow
  • (E,E)-1,7-Bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione (Natural)
  • Natural Yellow 3 (Natural)
  • (E,E)-1,7-Bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione (Synthetic)
  • 1,7-Bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione
  • C.I. Natural Yellow 3
  • Curcumin,AR
  • [ "" ]
  • Turmeric
  • Kacha haldi
  • Curcumin I
  • Halud
  • Haldar
  • Merita earth
  • Yellow Ginger
  • Terra Merita
  • Yellow Root
  • Safran d'Inde
  • Yo-Kin
  • Golden seal
  • Curcuma oil
  • Orange Root
  • Oils, curcuma
  • Curcumine
  • Hydrastis
  • Indian turmeric
  • Yellow puccoon
  • Diferaloylmethane
  • Kurkumin [Czech]
  • Tumeric yellow
  • Tur
  • Diferuloylmethane
  • Curcumin
  • TURMERIC OLEORESIN
  • TURMERIC OLEORESIN
  • TURMERIC OLEORESIN
  • CURCUMIN
  • CURCUMIN
  • CURCUMIN
  • MLS000069631
  • MLS000069631
  • MLS000069631
  • Natural yellow 3
  • Natural yellow 3
  • Natural yellow 3
  • CURCUMIN with HPLC [458-37-7]
  • CURCUMIN with HPLC [458-37-7]
  • CURCUMIN with HPLC [458-37-7]
  • Haidr Halud Halad Yo-Kin Haldar Souchet Curcuma CURCUMIN Gelbwurz Curcumin
  • Haidr Halud Halad Yo-Kin Haldar Souchet Curcuma CURCUMIN Gelbwurz Curcumin
  • Haidr Halud Halad Yo-Kin Haldar Souchet Curcuma CURCUMIN Gelbwurz Curcumin
  • E 100
  • E 100
  • E 100
  • [458-37-7]
  • [458-37-7]
  • [458-37-7]
  • SMR000058237
  • SMR000058237
  • SMR000058237
  • MLS001148449
  • MLS001148449
  • MLS001148449
  • CURCUMINE
  • CURCUMINE
  • CURCUMINE
  • ConMedNP.453
  • ConMedNP.453
  • ConMedNP.453
  • MLSMR
  • MLSMR
  • curcumin
  • MLSMR
  • curcumin
  • curcumin
  • MDL:MFCD00008365
  • InChIKey:VFLDPWHFBUODDF-FCXRPNKRSA-N
  • Inchi:1S/C21H20O6/c1-26-20-11-14(5-9-18(20)24)3-7-16(22)13-17(23)8-4-15-6-10-19(25)21(12-15)27-2/h3-12,24-25H,13H2,1-2H3/b7-3+,8-4+
  • SMILES:O(C([H])([H])[H])C1=C(C([H])=C([H])C(/C(/[H])=C(\[H])/C(C([H])([H])C(/C(/[H])=C(\[H])/C2C([H])=C([H])C(=C(C=2[H])OC([H])([H])[H])O[H])=O)=O)=C1[H])O[H]
  • BRN:2306965
Chemical and Physical Properties

Computed Properties

  • Exact Mass: 368.4g/mol
  • Surface Charge: 0
  • XLogP3: 3.2
  • Hydrogen Bond Donor Count: 2
  • Hydrogen Bond Acceptor Count: 6
  • Rotatable Bond Count: 8
  • Monoisotopic Mass: 368.125988g/mol
  • Monoisotopic Mass: 368.125988g/mol
  • Topological Polar Surface Area: 93.1Ų
  • Heavy Atom Count: 27
  • Complexity: 507
  • Isotope Atom Count: 0
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count : 0
  • Defined Bond Stereocenter Count: 2
  • Undefined Bond Stereocenter Count: 0
  • Covalently-Bonded Unit Count: 1
  • Tautomer Count: 51
  • XLogP4-AA: 3.2
  • Monoisotopic Mass: 368.125988
  • Regular Charging: 0
  • Topological Polar Surface Area: 93.1
  • Complexity: 507
  • Isotope Atom Count: 0
  • Functional 3D Acceptor Count: 4
  • Functional 3D Donor Count: 2
  • Functional 3D Anion Count: 1
  • Functional 3D ring Count: 2
  • Rotatable Bond Count: 8
  • RMSD: 1
  • CID conformational Count: 82
  • Surface Charge: 0

Experimental Properties

  • Stability Shelf Life: Stable under recommended storage conditions.
  • Decomposition: Hazardous decomposition products formed under fire conditions. - Carbon oxides
  • LogP: 3.85260
  • PSA: 96.22000
  • Merck: 2673
  • Refractive Index: n20/D 1.363
  • Water Partition Coefficient: Slightly soluble in water (hot)
  • Boiling Point: 593.2°C at 760 mmHg
  • Flash Point: Fahrenheit: 57.2 ° f
    Celsius: 14 ° c
  • Color/Form: ~0.1 % (w/v) (in ethanol with 2M HCl (99:1 v/v))
  • Stability/Shelf Life: Stable, but may be light sensitive. Incompatible with strong oxidizing agents.
  • Solubility: It is easily soluble in ethanol, propylene glycol, acetone, glacial acetic acid and alkaline solution. After dissolving in ethanol, it can be diluted with water, but insoluble in cold water and grease. Slightly soluble in ether.
  • pka: 8.09(at 25℃)
  • Color index: 75300
  • λmax: 430nm
  • PH: Yellow (7.8) to red-brown (9.2)
  • Refractive Index: INDEX OF REFRACTION: 1.5118 @ 20 °C/D; SPECIFIC 0PTICAL ROTATION: +14 DEG 4 MIN; SOL: 1:0.6 IN 90% ETHANOL /ESSENTIAL OIL OF CURCUMA LONGA/
Security Information
  • Symbol: GHS07
  • RTECS:MI5230000
  • WGK Germany:3
  • Safety Term:S26;S36
  • Safety Instruction:S26; S36
  • Risk Phrases:R36/37/38
  • Tanda barang berbahaya: Xi Xi
  • Hazardous Material transportation number:NONH for all modes of transport
  • Hazard Statement:H315,H319,H335
  • Warning Statement:P261,P305+P351+P338
  • Prompt:warning
  • Storage Condition:Powder -20°C 3 years   4°C 2 years In solvent -80°C 6 months   -20°C 1 month
  • PackingGroup:II
  • Hazard Category Code:36/37/38
  • Signal Word:Warning
  • TSCA:Yes
  • HazardClass:3
Customs Data
  • HS CODE:29145000
  • Customs Data:

    China Customs Code:

    2914509090

    Overview:

    2914509090 Ketones containing other oxygen-containing groups. VAT:17.0% Tax refund rate:9.0% Regulatory conditions:nothing MFN tariff:5.5% general tariff:30.0%

    Declaration elements:

    Product Name, component content, use to, Acetone declared packaging

    Summary:

    HS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

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T1516-500mg 97.51% 上海现货 500mg ¥ 545 07 Sep. 2023
T1516-100mg 97.51% 上海现货 100mg ¥ 373 07 Sep. 2023
T1516-1 mL * 10 mM (in DMSO) 97.51% 上海现货 1 mL * 10 mM (in DMSO) ¥485.00 26 Apr. 2022
T1516-500 mg 97.51% 上海现货 500MG ¥620.00 26 Apr. 2022
T1516-100 mg 97.51% 上海现货 100MG ¥440.00 26 Apr. 2022
Brand:scbt Supplier:圣克鲁斯生物技术
No. Purity Stock Specification Price update time operate
sc-294110A-25g ≥95% 25g ¥1128.00 05 Sep. 2023
sc-294110-5g ≥95% 5g ¥376.00 05 Sep. 2023
sc-200509E-2.5kg ≥95% 2.5kg ¥14440.00 05 Sep. 2023
sc-200509F-1kg ≥95% 1kg ¥6280.00 05 Sep. 2023
sc-200509D-250g ≥95% 250g ¥1655.00 05 Sep. 2023
sc-200509C-100g ≥95% 100g ¥827.00 05 Sep. 2023
sc-200509B-25g ≥95% 25g ¥451.00 05 Sep. 2023
sc-200509A-5g ≥95% 5g ¥286.00 05 Sep. 2023
sc-200509-1g ≥95% 1g ¥143.00 05 Sep. 2023
sc-200509E-2.5 kg ≥95% 2.5 kg ¥14,440.00 10 Jul. 2023
sc-200509F-1 kg ≥95% 1kg ¥6,280.00 10 Jul. 2023
sc-200509D-250 g ≥95% 250g ¥1,655.00 10 Jul. 2023
sc-200509C-100 g ≥95% 100g ¥827.00 10 Jul. 2023
sc-200509B-25 g ≥95% 25g ¥451.00 10 Jul. 2023
sc-200509A-5 g ≥95% 5g ¥286.00 10 Jul. 2023
sc-200509-1 g ≥95% 1g ¥143.00 10 Jul. 2023
sc-294110A-25 g ≥95% 25g ¥1,128.00 10 Jul. 2023
sc-294110-5 g ≥95% 5g ¥376.00 10 Jul. 2023
Brand:otavachemicals Supplier:OTAVAchemicals
No. Purity Stock Specification Price update time operate
15386368-5G 95% 5530mg 5G $150/ ¥1,089.48 06 Jul. 2023
15386368-2G 95% 5530mg 2G $125/ ¥907.90 06 Jul. 2023
15386368-1G 95% 5530mg 1G $100/ ¥726.32 06 Jul. 2023
Brand:lktlabs Supplier:LKT Labs
No. Purity Stock Specification Price update time operate
C8069-50 g ≥97% curcuminoid content In stock 50g $277.10 / ¥2,012.63 11 Jul. 2023
C8069-10 g ≥97% curcuminoid content In stock 10g $77.00 / ¥559.27 11 Jul. 2023
C8069-5 g ≥97% curcuminoid content In stock 5g $47.10 / ¥342.10 11 Jul. 2023
C8070-100 mg ≥98% In stock 100MG $648.30 / ¥4,708.73 11 Jul. 2023
C8070-25 mg ≥98% In stock 25mg $249.90 / ¥1,815.07 11 Jul. 2023
C8070-10 mg ≥98% In stock 10mg $120.30 / ¥873.76 11 Jul. 2023
Brand:ambeed Supplier:Ambeed
No. Purity Stock Specification Price update time operate
A147405-1kg 98% 中国:-/USA:- 1kg $213.0/ ¥1,547.06 20 Jun. 2023
A147405-500g 98% 中国:8/USA:2 500g $107.0/ ¥777.16 20 Jun. 2023
A147405-100g 98% 中国:11/USA:1 100g $29.0/ ¥210.63 20 Jun. 2023
A147405-25g 98% 中国:10/USA:5 25g $9.0/ ¥65.37 20 Jun. 2023
A147405-10g 98% 中国:5/USA:1 10g $6.0/ ¥43.58 20 Jun. 2023
A147405-5g 98% 中国:18/USA:7 5g $5.0/ ¥36.32 20 Jun. 2023
Brand:alfa Supplier:阿法埃莎,赛默飞世尔科技旗下公司
No. Purity Stock Specification Price update time operate
B21573-250g 95% 250g ¥8185.00 01 Mar. 2023
B21573-50g 95% 50g ¥1563.00 01 Mar. 2023
B21573-10g 95% 10g ¥643.00 01 Mar. 2023
Brand:Key Organics Supplier:Key Organics Ltd
No. Purity Stock Specification Price update time operate
AS-72202-10MG >97% Same Day Despatch 10mg £51.00/ ¥425.04 09 Sep. 2023
AS-72202-5MG >97% Same Day Despatch 5mg £42.00/ ¥350.04 09 Sep. 2023
AS-72202-1MG >97% Same Day Despatch 1mg £36.00/ ¥300.03 09 Sep. 2023
Brand:乐研 Supplier:上海皓鸿生物医药科技有限公司
No. Purity Stock Specification Price update time operate
1033031-1kg 98% 上海:6/安徽:9/武汉:> 10/成都:> 10/天津:/深圳: 1kg ¥ĸǡŞƆ 25 Jul. 2023
1033031-500g 98% 上海:> 10/安徽:> 10/武汉:1/成都:2/天津:/深圳: 500g ¥ȋȋĸ 25 Jul. 2023
1033031-100g 98% 上海:3/安徽:> 10/武汉:> 10/成都:> 10/天津:/深圳: 100g ¥ĸȋȋ 25 Jul. 2023
1033031-25g 98% 上海:> 10/安徽:> 10/武汉:> 10/成都:7/天津:/深圳: 25g ¥Ġdž 25 Jul. 2023
Brand:CityChemical Supplier:City Chemical
No. Purity Stock Specification Price update time operate
722D-10GM recrystallized,biostain 10gm $96.56/ ¥701.33 19 Sep. 2023
754B-5KG powder 5kg $2342.87/ ¥17,016.73 19 Sep. 2023
754B-1KG powder 1kg $572.70/ ¥4,159.63 19 Sep. 2023
754B-100GM powder 100gm $72.02/ ¥523.10 19 Sep. 2023
T1900-100GM indicator 100gm $120.49/ ¥875.14 19 Sep. 2023
T1900-50GM indicator 50gm $193.43/ ¥1,404.92 19 Sep. 2023
Brand:Biopurify Supplier:Chengdu Biopurify Phytochemicals Ltd
No. Purity Stock Specification Price update time operate
BP0421-20mg 98% 20mg $35/ ¥254.21 19 Sep. 2023
BP0421-1000mg 98% 1000mg $80/ ¥581.06 19 Sep. 2023
BP0421-100mg 98% 100mg $50/ ¥363.16 19 Sep. 2023
BP0421-20mg 98% 20mg $35/ ¥254.21 20 Sep. 2023
BP0421-1000mg 98% 1000mg $80/ ¥581.06 20 Sep. 2023
BP0421-100mg 98% 100mg $50/ ¥363.16 20 Sep. 2023
Brand:罗恩试剂 Supplier:上海易恩化学技术有限公司
No. Purity Stock Specification Price update time operate
R097046-100g 98% 现货 100g ¥167 08 Sep. 2023
R097046-25g 98% 现货 25g ¥54 08 Sep. 2023
R097046-5g 98% 现货 5g ¥35 08 Sep. 2023
R019728-20mg 分析对照品试剂 现货 20mg ¥123 08 Sep. 2023
R015675-5g AR 现货 5g ¥32 08 Sep. 2023
R015675-25g AR 现货 25g ¥42 08 Sep. 2023
R015675-100g AR 现货 100g ¥131 08 Sep. 2023
Brand:chemscene Supplier:ChemScence
No. Purity Stock Specification Price update time operate
CS-1490-1kg 97.06% In-stock 1kg $275.0/ ¥1,997.38 27 Apr. 2022
CS-1490-500g 97.06% In-stock 500g $145.0/ ¥1,053.16 27 Apr. 2022
CS-1490-500mg 96.31% In-stock 500mg $96.0/ ¥697.27 02 Sep. 2021
CS-1490-100mg 96.31% In-stock 100mg $60.0/ ¥435.79 02 Sep. 2021
Brand:apolloscientific Supplier:Apollo Scientific
No. Purity Stock Specification Price update time operate
OR24598-100g 97% US:Out of Stock/UK:In Stock 100g £92.00/ ¥766.75 02 Sep. 2023
OR24598-25g 97% US:Out of Stock/UK:In Stock 25g £33.00/ ¥275.03 02 Sep. 2023
OR24598-5g 97% US:Out of Stock/UK:In Stock 5g £18.00/ ¥150.02 02 Sep. 2023
BIC8500-100g 97% US:Out of Stock/UK:2 Packs in stock. 100g £92.00/ ¥766.75 01 Sep. 2023
BIC8500-25g 97% US:Out of Stock/UK:In Stock 25g £33.00/ ¥275.03 01 Sep. 2023
BIC8500-5g 97% US:Out of Stock/UK:In Stock 5g £18.00/ ¥150.02 01 Sep. 2023
Brand:labchem Supplier:FUJIFILM
No. Purity Stock Specification Price update time operate
031-21991-10mg In stock in Japan 10mg JPY 37800/ ¥1,857.11 15 Sep. 2023
Brand:安捷凯 Supplier:武汉安捷凯生物医药科技有限公司
No. Purity Stock Specification Price update time operate
ajci13816-100mg 98% 现货 100mg ¥428.00 09 Sep. 2023
Brand:源叶 Supplier:上海源叶生物科技有限公司
No. Purity Stock Specification Price update time operate
B20614-1g 分析标准品,HPLC≥98% 上海:准现货/北京:0/武汉:0/南京:0 1g ¥3200.00 07 Jan. 2022
B20614-500mg 分析标准品,HPLC≥98% 上海:准现货/北京:0/武汉:0/南京:0 500mg ¥2000.00 07 Jan. 2022
B20614-20mg 分析标准品,HPLC≥98% 上海:>10/北京:8/武汉:0/南京:0 20mg ¥200.00 07 Jan. 2022
Brand:trc Supplier:TRC
No. Purity Stock Specification Price update time operate
C838500-50g 0.0 50g $305.00/ ¥2,215.28 18 May. 2023
C838500-25g 0.0 25g $170.00/ ¥1,234.74 18 May. 2023
C838500-10g 0.0 10g $ 97.00/ ¥704.53 08 Sep. 2023
C838500-5g 0.0 5g $92.00/ ¥668.21 18 May. 2023
C838500-1g 0.0 1g $ 85.00/ ¥617.37 08 Sep. 2023
C838500-50mg 0.0 50mg $ 74.00/ ¥537.48 08 Sep. 2023
Brand:bomeibio Supplier:合肥博美生物科技有限责任公司
No. Purity Stock Specification Price update time operate
JC3964-5g ≥97% 现货 5g ¥130.00元 15 Sep. 2023
JC3964-25g ≥97% 现货 25g ¥450.00元 15 Sep. 2023
JC3964-100g ≥97% 现货 100g ¥1420.00元 15 Sep. 2023
JC1739-5g ≥90% 现货 5g ¥50元 15 Sep. 2023
JC1739-25g ≥90% 现货 25g ¥120元 15 Sep. 2023
JC1739-100g ≥90% 现货 100g ¥430元 15 Sep. 2023
BZP0086-20mg HPLC≥98% 现货 20mg ¥160元 15 Sep. 2023
Brand:a2bchem Supplier:A2B Chem LLC
No. Purity Stock Specification Price update time operate
AB51052-5g 98% in stock 5g $4.00/ ¥29.05 30 Dec. 2023
AB51052-10g 98% in stock 10g $5.00/ ¥36.32 30 Dec. 2023
AB51052-25g 98% in stock 25g $7.00/ ¥50.84 30 Dec. 2023
AB51052-100g 98% in stock 100g $21.00/ ¥152.53 30 Dec. 2023
AB51052-500g 98% in stock 500g $75.00/ ¥544.74 30 Dec. 2023
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