1.1
Reagents:
Tetrabutylammonium chloride
Solvents:
Acetonitrile
;
rt → 0 °C
1.2
Reagents:
N,N-Dimethylaniline
,
Phosphorus oxychloride
;
1 h, 70 °C
1.3
Reagents:
Sodium bicarbonate
Solvents:
Dichloromethane
,
Water
;
rt
1.4
Solvents:
Methanol
,
Water
;
1.5 h, -5 °C
1.1
Reagents:
Benzyltriethylammonium chloride
,
N,N-Dimethylaniline
,
Phosphorus oxychloride
Solvents:
Acetonitrile
;
0 °C; 1.5 h, 70 °C
1.2
Solvents:
Methanol
,
Water
;
1.5 h, 0 °C