(2-溴苯基-1,3,5-三基)三环己烷 | 97443-80-6
中文名称:
(2-溴苯基-1,3,5-三基)三环己烷
英文名称:
1-Bromo-2,4,6-tricyclohexylbenzene
CAS No.:
97443-80-6
分子式:
C2 4 H3 5 Br
分子量:
403.438706636429
名称和标识符
MDL
MFCD22370173
InChIKey
WAMFJXQPJPAGHX-UHFFFAOYSA-N
Inchi
1S/C24H35Br/c25-24-22(19-12-6-2-7-13-19)16-21(18-10-4-1-5-11-18)17-23(24)20-14-8-3-9-15-20/h16-20H,1-15H2
SMILES
BrC1C(C2CCCCC2)=CC(C2CCCCC2)=CC=1C1CCCCC1
别名信息
- 中文别名 -
(2-溴苯基-1,3,5-三基)三环己烷
1,3,5-三环己基溴苯
- 英文别名 -
Benzene, 2-bromo-1,3,5-tricyclohexyl-
1-Bromo-2,4,6-tricyclohexylbenzene
2-bromo-1,3,5-tricyclohexylbenzene
2,4,6-Tricyclohexylbromobenzene
2,4,6-Tricyclohexylphenyl bromide
2-Bromo-1,3,5-tricyclohexylbenzene (ACI)
1,3,5-Tricyclohexylbromobenzene
2-Bromo-1,3,5-tricyclohexylbenzene
合成路线
合成路线:1 步
1.1
Reagents:
Bromine
Solvents:
Chloroform
;
2 h, 0 °C
参考文献:
Organocatalytic Kinetic Resolution of Sulfoximines
Dong, Shunxi;
Frings, Marcus;
Cheng, Hanchao;
Wen, Jian;
Zhang, Duo; et al ,
Journal of the American Chemical Society ,
2016 ,
138(7) ,
2166-2169
合成路线:1 步
参考文献:
Mesomeric dipole moments. VII. Secondary steric effects in 2,4,6-trialkylated acetophenones and nitrobenzenes: dipole moments and carbon-13 NMR spectra
Koudelka, Juraj;
Saman, David;
Exner, Otto ,
Collection of Czechoslovak Chemical Communications ,
1985 ,
50(1) ,
208-14
合成路线:1 步
1.1
Reagents:
N-Bromosuccinimide
Solvents:
Acetonitrile
,
Dichloromethane
;
30 min, 0 °C; 0 °C → rt; 12 h, rt
参考文献:
Chemically amplified resist composition and pattern forming process having high resolution and minimal line edge roughness
,
United States ,
,
,
合成路线:1 步
1.1
Reagents:
Bromine
Solvents:
Chloroform
;
10 min, rt → 0 °C; 0 °C → rt; 2 h, rt
1.2
Reagents:
Sodium sulfite
Solvents:
Dichloromethane
,
Water
;
rt
参考文献:
Enantioselective Halogenative Semi-Pinacol Rearrangement: Extension of Substrate Scope and Mechanistic Investigations
Romanov-Michailidis, Fedor;
Romanova-Michaelides, Maria;
Pupier, Marion;
Alexakis, Alexandre ,
Chemistry - A European Journal ,
2015 ,
21(14) ,
5561-5583
合成路线:1 步
1.1
Reagents:
Bromine
Solvents:
Chloroform
;
15 min, 0 °C; 0 °C → 40 °C; 3 h, 40 °C
参考文献:
An Alternative Synthesis of Cycloalkyl-Substituted CPA Catalysts and Application in Asymmetric Protonation Reactions
McLean, Liam A.
;
Watson, Allan J. B. ,
European Journal of Organic Chemistry ,
2021 ,
2021(35) ,
4943-4945
合成路线:1 步
1.1
Reagents:
Bromine
Solvents:
Chloroform
;
10 min, 0 °C; 0 °C → rt; 2 h, rt
1.2
Reagents:
Sodium sulfite
Solvents:
Dichloromethane
,
Water
参考文献:
Enantioselective Organocatalytic Fluorination-Induced Wagner-Meerwein Rearrangement
Romanov-Michailidis, Fedor;
Guenee, Laure;
Alexakis, Alexandre ,
Angewandte Chemie ,
2013 ,
52(35) ,
9266-9270
合成路线:1 步
1.1
Reagents:
Bromine
Solvents:
Chloroform
;
15 min, 0 °C; 0 °C → rt; 2 h, rt
参考文献:
A New Biarylphosphine Ligand for the Pd-Catalyzed Synthesis of Diaryl Ethers under Mild Conditions
Salvi, Luca;
Davis, Nicole R.;
Ali, Siraj Z.;
Buchwald, Stephen L. ,
Organic Letters ,
2012 ,
14(1) ,
170-173
合成路线:1 步
1.1
Reagents:
Aluminum chloride
;
5 min, -40 °C; 30 min, -40 °C → rt
1.2
Reagents:
Sodium bicarbonate
Solvents:
Hexane
,
Water
1.3
Reagents:
Bromine
Solvents:
Trimethyl phosphate
;
5 min, 70 °C; 1.5 h, 70 °C
参考文献:
Enantioselective Synthesis of Highly Substituted Furans by a Copper(II)-Catalyzed Cycloisomerization-Indole Addition Reaction
Rauniyar, Vivek;
Wang, Z. Jane;
Burks, Heather E.;
Toste, F. Dean ,
Journal of the American Chemical Society ,
2011 ,
133(22) ,
8486-8489
合成路线:1 步
1.1
Reagents:
Bromine
Solvents:
Chloroform
;
0 °C; 0 °C → rt; 20 h, rt
参考文献:
Direct catalytic asymmetric synthesis of α-chiral bicyclo[1.1.1]pentanes
Wong, Marie L. J.;
Sterling, Alistair J.
;
Mousseau, James J.;
Duarte, Fernanda
;
Anderson, Edward A. ,
Nature Communications ,
2021 ,
12(1) ,