找化学品上960化工网!
960化工网

4-甲基-1-哌嗪乙胺 | 934-98-5

4-甲基-1-哌嗪乙胺
2-(4-methylpiperazin-1-yl)ethan-1-amine
934-98-5
C7H17N3
143.229981184006
如需查看该化合物的详细结构式,mol文件,smile,InChi 请点击:4-甲基-1-哌嗪乙胺结构式
70284
名称和标识符
MDL MFCD03701701
InChIKey GOWUDHPKGOIDIX-UHFFFAOYSA-N
Inchi 1S/C7H17N3/c1-9-4-6-10(3-2-8)7-5-9/h2-8H2,1H3
SMILES NCCN1CCN(C)CC1
别名信息
- 中文别名 -
  • 4-甲基-1-哌嗪乙胺
  • 1-(2-氨乙基)-4-甲基哌嗪
  • 2-(4-甲基-1-哌嗪基)乙胺
  • 2-(4-甲基-哌嗪-1-基)乙胺
  • 1-(N-胺乙基)-4-甲基哌嗪
  • 2-(4-甲基-哌嗪基)-4-甲基
- 英文别名 -
  • 2-(4-Methylpiperazin-1-yl)ethylamine
  • 1-(2-Aminoethyl)-4-methylpiperazine
  • 1-(2-Aminoethyl)-4-Methyl-Piperazine
  • 2-(4-Methylpiperazin-1-yl)ethanamine
  • 2-(4-Methyl-piperazin-1-yl)-ethylamine
  • 4-Methyl-1-piperazineethanamine
  • 1-Piperazineethanamine,4-methyl
  • 4-Methyl-1-piperazineethanamine (ACI)
  • Piperazine, 1-(2-aminoethyl)-4-methyl- (6CI, 7CI, 8CI)
  • 1-Methyl-4-(2-aminoethyl)piperazine
  • 2-(4-Methyl-1-piperazinyl)ethanamine
  • 2-(4-Methylpiperazin-1-yl)ethan-1-amine
  • 2-(4-Methylpiperazino)ethanamine
  • 4-(2-Aminoethyl)-1-methylpiperazine
物化性质
实验特性
LogP -0.23140
PSA 32.50000
沸点 215.4℃ at 760 mmHg
敏感性 Air Sensitive
计算特性
精确分子量 143.14200
氢键供体数量 1
氢键受体数量 3
可旋转化学键数量 2
重原子数量 10
复杂度 86.9
同位素原子数量 0
确定原子立构中心数量 0
不确定原子立构中心数量 0
确定化学键立构中心数量 0
不确定化学键立构中心数量 0
共价键单元数量 1
疏水参数计算参考值(XlogP) -0.9
互变异构体数量
表面电荷 0
海关数据
海关编码 2933599090
海关数据

中国海关编码:

2933599090

概述:

2933599090. 其他结构上有嘧啶环的化合物(包括其他结构上有哌嗪环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

申报要素:

品名, 成分含量, 用途, 乌洛托品请注明外观, 6-己内酰胺请注明外观, 签约日期

Summary:

2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

合成路线

合成路线:1 步

反应条件:
参考文献:
Synthesis and antitumor activity of 5-bromo-7-azaindolin-2-one derivatives containing a 2,4-dimethyl-1H-pyrrole-3-carboxamide moiety
Zhang, Jun; Shen, Weiyi; Li, Xiaoning; Chai, Yun; Li, Senjun; et al, Molecules, 2016, 21(12), 1674-1683

合成路线:1 步

反应条件:
参考文献:
New derivatives of quinoline-4-carboxylic acid with antiplasmodial activity
Hochegger, Patrick ; Faist, Johanna; Seebacher, Werner; Saf, Robert; Maeser, Pascal; et al, Bioorganic & Medicinal Chemistry, 2017, 25(7), 2251-2259

合成路线:1 步

反应条件:
参考文献:
Phenyl-urea and phenyl-carbamate derivatives as inhibitors of protein aggregation
, World Intellectual Property Organization, , ,

合成路线:1 步

反应条件:
参考文献:
New pyrido[3,4-g]quinazoline derivatives as CLK1 and DYRK1A inhibitors: synthesis, biological evaluation and binding mode analysis
Tazarki, Helmi ; Zeinyeh, Wael; Esvan, Yannick J.; Knapp, Stefan; Chatterjee, Deep; et al, European Journal of Medicinal Chemistry, 2019, 166, 304-317

合成路线:1 步

反应条件:
参考文献:
Structural optimizations and bioevaluation of N-substituted acridone derivatives as strong topoisomerase II inhibitors
Li, Zhi-Ying; Xu, Guang-Sen; Song, Yu-Liang; Li, Xun, Bioorganic Chemistry, 2022, 119,

合成路线:1 步

反应条件:
参考文献:
Drug containing cinnamic acid amide, especially for chronic pain treatment
, Japan, , ,

合成路线:1 步

反应条件:
参考文献:
Preparation of cinnamic acid amide derivatives as analgesics
, World Intellectual Property Organization, , ,

合成路线:1 步

反应条件:
参考文献:
Synthesis and evaluation of chirally defined side chain variants of 7-chloro-4-aminoquinoline to overcome drug resistance in malaria chemotherapy
Dola, Vasantha Rao; Soni, Awakash; Agarwal, Pooja; Ahmad, Hafsa; Raju, Kanumuri Siva Rama; et al, Antimicrobial Agents and Chemotherapy, 2017, 61(3),

合成路线:1 步

反应条件:
参考文献:
2,3-Dihydro-2-oxo-1H-benzimidazole-1-carboxamides with Selective Affinity for the 5-HT4 Receptor: Synthesis and Structure-Affinity and Structure-Activity Relationships of a New Series of Partial Agonist and Antagonist Derivatives
Tapia, Ines; Alonso-Cires, Luisa; Lopez-Tudanca, Pedro Luis; Mosquera, Ramon; Labeaga, Luis; et al, Journal of Medicinal Chemistry, 1999, 42(15), 2870-2880

合成路线:1 步

反应条件:
参考文献:
Guanidines having antihypertensive activity. I. Dialkylaminoalkylamino-2-imidazolines
Najer, Henry; Giudicelli, Rene; Sette, Jacques, Bulletin de la Societe Chimique de France, 1962, 556, 556-9

合成路线:1 步

反应条件:
参考文献:
Preparation of aminoquinoline derivatives for use as antimalarials
, India, , ,

合成路线:1 步

反应条件:
参考文献:
Synthesis and cytotoxicity of novel indirubin-5-carboxamides
Cheng, Xinlai; Rasque, Paul; Vatter, Sandra; Merz, Karl-Heinz; Eisenbrand, Gerhard, Bioorganic & Medicinal Chemistry, 2010, 18(12), 4509-4515
专业数据库参考
PubChemId 70284
960化工网为您提供4-甲基-1-哌嗪乙胺专业化合物百科信息,包括中文名,英文名,分子式,分子量,以及该化合物的CasNo.:934-98-5,和相关理化性质;并提供了优质生产厂家信息包括厂家名称和联系方式等;| WAP 版:934-98-5
平台客服 平台客服

平台在线客服