2931900090. other organo-inorganic compounds. VAT:17.0%. Tax rebate rate:13.0%. Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward). MFN tariff:6.5%. General tariff:30.0%
Discovery of the PARP (poly ADP-ribose polymerase) inhibitor 2-(1-(4,4-difluorocyclohexyl)piperidin-4-yl)-1H-benzo[d]imidazole-4-carboxamide for the treatment of cancer
Fluorine-containing substituted benzimidazole derivatives and their application in preparing drugs for prevention and treatment of PARP (poly (ADP-ribose) polymerase)-related diseases
Bronsted Acid or Lewis Acid Catalyzed [3+3] Cycloaddition of Azomethine Imines with N-Benzyl Azomethine Ylide: A Facile Access to Bicyclic N-Heterocycles
Discovery of 2-(1-(3-(4-chloroxyphenyl)-3-oxo- propyl)pyrrolidine-3-yl)-1H-benzo[d]imidazole-4-carboxamide: a potent poly(ADP-ribose) polymerase (PARP) inhibitor for treatment of cancer
Chemistry of organosilicon compounds. 195. N-(Trimethylsilylmethyl)aminomethyl ethers as azomethine ylide synthons. A new and convenient access to pyrrolidine derivatives
Preparation of 1,2,3,3a,8,8a-hexahydro-2,7a-diazacyclopenta[a]inden-7-ones and related compounds as nicotinic acetylcholine receptor ligands useful in modulating cholinergic function and in the treatment of addictive disorders
1.1
Reagents:
Potassium carbonate
Solvents:
Water
;
16 h, 0 - 25 °C
参考文献:
Design, synthesis, and validation of a β-turn mimetic library targeting protein-protein and peptide-receptor interactions
Whitby, Landon R.;
Ando, Yoshio;
Setola, Vincent;
Vogt, Peter K.;
Roth, Bryan L.; et al,
Journal of the American Chemical Society,
2011,
133(26),
10184-10194
1.1
Solvents:
Water
;
10 min, 0 °C; 2 h, 0 °C 1.2
Reagents:
Potassium carbonate
;
30 min, 0 °C
参考文献:
Stereo-, Regio-, and Chemoselective [3 + 2]-Cycloaddition of (2E,4E)-Ethyl 5-(Phenylsulfonyl)penta-2,4-dienoate with Various Azomethine Ylides, Nitrones, and Nitrile Oxides: Synthesis of Pyrrolidine, Isoxazolidine, and Isoxazoline Derivatives and a Computational Study
Sankar, Ulaganathan;
Surya Kumar, Ch. Venkata;
Subramanian, V.;
Balasubramanian, K. K.;
Mahalakshimi, S.,
Journal of Organic Chemistry,
2016,
81(6),
2340-2354