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甲基强的松龙 | 83-43-2

甲基强的松龙结构式图片|83-43-2结构式图片 →现货商城 点击进入
中文名称：甲基强的松龙
英文名称：Methylprednisolone
CAS No.：83-43-2 分子式：C22H30O5 分子量：374.4706
如需查看该化合物的详细结构式,mol文件,smile, InChi 请点击：甲基强的松龙结构式
MSDS：甲基强的松龙msds 价格行情：甲基强的松龙价格 PubChem CID：24896564
国内供应商
甲基强的松龙的其他展现形式
  • 相关化合物
羟孕酮
羟孕酮 17A-hydroxyprogesterone CAS No.：68-96-2
泼尼松龙
泼尼松龙 prednisolone CAS No.：50-24-8
泼尼松
泼尼松 prednisone CAS No.：53-03-2
帕拉米松
帕拉米松 Paramethasone CAS No.：53-33-8
氟泼尼龙
氟泼尼龙 Fluprednisolone CAS No.：53-34-9
醋酸泼尼松龙
醋酸泼尼松龙 prednisolone acetate CAS No.：52-21-1
简介
Methylprednisolone 是皮质类固醇，可作用于糖皮质激素受体。Methylprednisolone 通过激活 ACE2 并降低 IL-6 水平来改善严重的 COVID-19。
名称和标识符
MDL MFCD00010591
InChIKey VHRSUDSXCMQTMA-PJHHCJLFSA-N
Inchi 1S/C22H30O5/c1-12-8-14-15-5-7-22(27,18(26)11-23)21(15,3)10-17(25)19(14)20(2)6-4-13(24)9-16(12)20/h4,6,9,12,14-15,17,19,23,25,27H,5,7-8,10-11H2,1-3H3/t12-,14-,15-,17-,19+,20-,21-,22-/m0/s1
SMILES O([H])[C@]1(C(C([H])([H])O[H])=O)C([H])([H])C([H])([H])[C@@]2([H])[C@]3([H])C([H])([H])[C@]([H])(C([H])([H])[H])C4=C([H])C(C([H])=C([H])[C@]4(C([H])([H])[H])[C@@]3([H])[C@]([H])(C([H])([H])[C@@]21C([H])([H])[H])O[H])=O
别名信息
- 中文别名 -
甲基氢化泼尼松 甲基强的松龙 甲基泼尼松龙 甲泼尼龙 甲强龙 6α-甲基强的松龙 六甲基泼尼松龙 皮質[甾]酮 6a甲基泼尼松龙 6-A-甲基泼尼松龙 6a-甲基泼尼松龙 6-α-甲基泼尼松标准品 6α-甲基泼尼松龙 6-α-甲基泼尼松龙-D4 甲醇中甲基泼尼松龙溶液标准物质 甲基泼尼松龙 标准品 甲基泼尼松龙(6α-甲基泼尼松龙) 甲基泼尼松龙标准溶液 甲基强的松龙,USP,BP,EP 甲基强的松龙标准品 甲基氢化泼尼松原药 甲泼尼龙 USP标准品 炔雌醇中间体 11β,17α,21-三羟基-6α-甲基-1,4-孕甾二烯-3,20-二酮 11β,17α,21-三羟基-6α-甲基-1,4-孕甾二烯-3,20-二酮 6α-甲基-11β,17α,21-三羟基-1,4-孕甾二烯-3,20-二酮 6α-甲基泼尼松龙 甲基强的松龙 甲基泼尼松龙 6α-甲基-11β,17α,21-三羟基-1,4-孕甾二烯-3,20-二酮 甲基泼尼松龙醋酸酯杂质B(EP) 甲基泼尼松龙琥珀酸钠杂质A(EP) 标准品
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- 英文别名 -
6alpha-methylprednisolone Methylprednisolone 11-beta,17-alpha,21-trihydroxy-6-alpha-methylpregna-1,4-diene-3,20-dione 6-methyl prednisolone acetate 6-α-Methylprednisolone (6S,8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-6,10,13-trimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one 6α-Methyl Prednisolo 6α-Methyl Prednisolone 6-α-Methylprednisolone Solution Methylprednisolone & Salts METHYLPREDNISOLONE, USP Metilprednisolone U 7532 11β,17α,21-Trihydroxy-6α-methyl-1,4-pregnadiene-3,20-dione 11b,17a,21-Trihydroxy-6a-methyl-1,4-pregnene-3,20-dione 6alpha-Methyl-1,4-pregnadiene-11beta,17alpha,21-triol-3,20-dione Medrol Medrone Urbason Metilbetasone Medrate Dopomedrol Promacortine Wyacort Urbasone Metrisone Medesone Besonia Metastab Mesopren Solomet Noretona Moderin Methylprednisolon Metrocort Methyleneprednisolone Suprametil Sieropresol Metysolon Esametone Reactenol Firmacort Medixon Nirypan Lemod Artisone-wyeth Medrol dosepak 6-alpha-Methylprednisolone Medrol adt pak Predni N Tablinen Medlone 21 Metilprednisolone [DCIT] Summicort M 11beta,17alpha,21-Trihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione Prednol-L 6alpha-Methyl-11beta,17alpha,21-triol-1,4-pregnadiene-3,20-dione HMS2230D16 SPBio_002377 SR-01000003089-2 MEPRDL METHYLPREDNISOLONE HYDROGEN SUCCINATE IMPURITY A [EP IMPURITY] METHYLPREDNISOLONE [GREEN BOOK] SCHEMBL5084 HSDB 3127 METHYLPREDNISOLONE (MART.) Methylprednisolone, British Pharmacopoeia (BP) Reference Standard Prednisolone, 6.alpha.-methyl- Medrol (TN) BRN 2340300 Pregna-1,4-diene-3,20-dione, 11,17,21-trihydroxy-6-methyl-, (6alpha,11beta)- 11beta,17,21-Trihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione methylprenisolone Prednisolone, 6alpha-methyl- DTXCID903300 NSC19987 METHYLPREDNISOLONE [EP MONOGRAPH] NSC-19987 Metilprednisolona [INN-Spanish] NC00691 MLS002207191 METHYLPREDNISOLONE [HSDB] Tox21_110376 Methylprednisolone, Pharmaceutical Secondary Standard Certified Reference Material Veriderm Medrol HMS2090B13 Methylprednisolonum [INN-Latin] BRD-K35240538-001-03-1 83-43-2 METHYLPREDNISOLONE [INN] Pregna-1,4-diene-3,20-dione, 11,17,21-trihydroxy-6-methyl-,(6.alpha.,11.beta.)- METHYLPREDNISOLONE [ORANGE BOOK] 6-methyl-prednisolone Prestwick3_000279 EC 201-476-4 Solu-Medrol (sodium succinate) NCI60_001657 EINECS 201-476-4 GTPL7088 METHYLPREDNISOLONE [JAN] AKOS015969744 NCGC00016330-01 1,4-pregnadien-6alpha-methyl-11beta, 17, 21-triol-3, 20-dione 6alpha-Methylprednisolone base Solpredone (6alpha,11beta)-11,17,21-Trihydroxy-6-methylpregna-1,4-diene-3,20-dione Pregna-1,20-dione, 11.beta.,17,21-trihydroxy-6.alpha.-methyl- SR-01000003089 Prestwick2_000279 6.alpha.-Methylprednisolone 1-dehydro-6-alpha-methylhydrocortisone 11?,17?,21-Trihydroxy-6?-methyl-1,4-pregnadiene-3,20-dione Pregna-1,4-dieno-3,20-diona, 11,17,21-trihidroxi-6-metil-, (6alfa, 11beta)- methylprednisolone Summicort 11beta,17alpha,21-Trihydroxy-6alpha-methyl-1,4-pregnadiene-3,20-dione BPBio1_000174 Pregna-1,20-dione, 6.alpha.-methyl-11.beta.-17,21-trihydroxy- HMS1568H20 CHEBI:6888 NCGC00255269-01 Metilbetasone Solubile LS-118498 (6?,11?)-11,17,21-Trihydroxy-6-methylpregna-1,4-diene-3,20-dione DB00959 A-Methapred Depo-Nisolone METHYLPREDNISOLONE [USP MONOGRAPH] HMS2095H20 6 Methylprednisolone (1R,3aS,3bS,5S,9aR,9bS,10S,11aS)-1,10-dihydroxy-1-(2-hydroxyacetyl)-5,9a,11a-trimethyl-1H,2H,3H,3aH,3bH,4H,5H,7H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-7-one MLS001148159 METHYLPREDNISOLONE (EP MONOGRAPH) 11-beta,17,21-Trihydroxy-6-alpha-methylpregna-1,4-diene-3,20-dione Meprolone Prestwick_622 Tox21_302018 DRG-0050 CAS-83-43-2 Methylprednisolone (JP17/USP/INN) METHYLPREDNISOLONE (USP-RS) Prednol- L (6-alpha,11-beta)-11,17,21-Trihydroxy-6-methylpregna-1,4-diene-3,20-dione SMR000058330 Pregna-1,20-dione, 11,17,21-trihydroxy-6-methyl-, (6.alpha.,11.beta.)- Prestwick1_000279 NCGC00022735-03 6alpha-Methylprednisolone, VETRANAL(TM), analytical standard (6S,8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-6,10,13-trimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one .DELTA.1-6.alpha.-Methylhydrocortisone Q417222 1-Dehydro-6alpha-methylhydrocortisone Predni-M-Tablinen LMST02030178 HY-B0260 METHYLPREDNISOLONE COMPONENT OF NEO-MEDROL 6-alpha-Methylprednisolone 100 microg/mL in Acetonitrile 4-08-00-03498 (Beilstein Handbook Reference) s1733 Methylprednisolone [USAN:INN:BAN:JAN] DTXSID7023300 Radilem KS-1273 Tox21_110376_1 Pregna-1,4-diene-3,20-dione, 11,17,21-trihydroxy-6-methyl-, (6.alpha.,11.beta.)- Prestwick0_000279 Methylprednisolone [USP:INN:BAN:JAN] Prednilen CCG-220279 C16437 11beta,17,21-trihydroxy-6alpha-methyl-1,4-pregnadiene-3,20-dione Metilprednisolona Methylprednisolone, 6-alpha Methylprednisolonum delta(1)-6alpha-Methylhydrocortisone Prednisolone, methyl- Methylprednisolone, United States Pharmacopeia (USP) Reference Standard NEO-MEDROL COMPONENT METHYLPREDNISOLONE Mega-Star X4W7ZR7023 VHRSUDSXCMQTMA-PJHHCJLFSA-N METHYLPREDNISOLONE [MART.] MLS002638721 BDBM50103616 UNII-X4W7ZR7023 MLS000028541 6alpha-Methylprednisolone, >=98% Methylprednisolone for system suitability A, EuropePharmacopoeia (EP) Reference Standard METHYLPREDNISOLONE [VANDF] M1665 medralone CHEMBL650 BSPBio_000158 6alpha-Methyl-11beta,17alpha,21-trihydroxy-1,4-pregnadiene-3,20-dione BRD-K35240538-001-26-2 EN300-7414014 Methylprednisolone [USAN:BAN:INN:JAN] METHYLPREDNISOLONE (USP MONOGRAPH) Pregna-1,4-diene-3,20-dione, 11,17,21-trihydroxy-6-methyl-, (6I+/-,11I(2))- Depo Moderin A855290 NCGC00022735-06 Pregna-1,4-diene-3,20-dione, 6-alpha-methyl-11-beta-17,21-trihydroxy- 6alpha-Methylprednisolone Methylprednisolone, European Pharmacopoeia (EP) Reference Standard METHYLPREDNISOLONE [MI] BRD-K35240538-001-11-4 Metipred DepMedalone HMS3712H20 METHYLPREDNISOLONE ACETATE IMPURITY B [EP IMPURITY] Opera_ID_1576 D08PIQ Pregna-1,4-diene-3,20-dione, 11beta,17,21-trihydroxy-6alpha-methyl- Caberdelta M D00407 Pregna-1,4-diene-3,20-dione, 11,17,21-trihydroxy-6-methyl-, (6a,11b)- (6a,11b)-11,17,21-Trihydroxy-6-methylpregna-1,4-diene-3,20-dione delta(sup 1)-6-alpha-Methylhydrocortisone METHYLPREDNISOLONE [WHO-DD] Methylprednisolone for system suitability, European Pharmacopoeia (EP) Reference Standard Duralone METHYLPREDNISOLONE [USP-RS] HMS3259J04 Q-201395 J3.872E Depo-Medrol (acetate)
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物化性质
 实验特性
LogP 1.80360
PSA 94.83000
Merck 14,6111
折射率 82 ° (C=1, Dioxane)
沸点 423.47°C (rough estimate)
熔点 228-237 ºC (dec.)
蒸气压 0.0±3.6 mmHg at 25°C
闪点 571.8 °C at 760 mmHg
溶解度 chloroform/methanol (9:1): 50 mg/mL, clear, faintly yellow
颜色与性状 Powder
溶解性 略微溶于乙醇、二氧六环、甲醇，微溶于丙酮、氯仿，极微溶于乙醚，不溶于水
敏感性 对光敏感
比旋光度 D20 +83° (dioxane)
密度 1.0868 (rough estimate)
 计算特性
精确分子量 374.20900
氢键供体数量 3
氢键受体数量 5
可旋转化学键数量 2
同位素质量 374.209
重原子数量 27
复杂度 754
同位素原子数量 0
确定原子立构中心数量 8
不确定原子立构中心数量 0
确定化学键立构中心数量 0
不确定化学键立构中心数量 0
共价键单元数量 1
疏水参数计算参考值（XlogP） 1.9
互变异构体数量 9
表面电荷 0
拓扑分子极性表面积 94.8
国际标准相关数据
EINECS 201-476-4
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专业数据库参考
PubChemId 24896564
参考资料
Beilstein 2340300
化合物详情（旧版）

甲基氢化泼尼松物理化学性质

熔点 228-237 ºC (DEC.)

甲基氢化泼尼松产品用途

适用于风湿性关节炎、胶原病、过敏性疾病、眼科疾患、淋巴白血病、软组织炎症及溶血性贫血等

应用领域





化学品安全说明书(MSDS)


储运特性



产品用途
适用于风湿性关节炎、胶原病、过敏性疾病、眼科疾患、淋巴白血病、软组织炎症及溶血性贫血等
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6a-甲基泼尼松龙，甲强龙，甲泼尼龙，甲基泼尼松龙
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与甲基强的松龙相关的问答
  1. 甲基强的松龙是什么？
  2. 强的松龙就是强的松吗?
  3. 「甲基强的松龙」有哪些品牌？
  4. 强的松，促肾上腺素，地塞米松，甲基强的松龙
  5. 醋酸强的松龙作用
  6. 有人用过甲基强的松龙吗？
  7. 甲基强的松龙影响儿童发育吗
  8. 甲基强的松龙的熔点是多少？
  9. 强的松和强的松龙有何区别？
  10. 甲基强的松龙冲击治疗方法为

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