1.1
Catalysts:
Phenyl borate
,
(1S)-3,3′-Dibromo[1,1′-binaphthalene]-2,2′-diol
Solvents:
(Trifluoromethyl)benzene
;
2 h, 80 °C
1.2
2 d, 80 °C; 80 °C → rt
1.3
Reagents:
Sodium bicarbonate
Solvents:
Methanol
,
Water
;
12 h, rt
1.4
Solvents:
Water
;
pH 7, rt
1.5
Reagents:
Ethanamine, N,N-diethyl-, hydrofluoride (1:1)
Solvents:
Acetonitrile
;
0 °C → rt; 12 h, rt