MDL | MFCD06410948 |
InChIKey | SWIROVJVGRGSPO-JBVRGBGGSA-N |
Inchi | 1S/C42H72O13/c1-21(2)10-9-14-42(8,55-37-35(51)33(49)31(47)25(20-44)53-37)22-11-16-41(7)29(22)23(45)18-27-39(5)15-13-28(38(3,4)26(39)12-17-40(27,41)6)54-36-34(50)32(48)30(46)24(19-43)52-36/h10,22-37,43-51H,9,11-20H2,1-8H3/t22-,23+,24+,25+,26-,27+,28-,29-,30+,31+,32-,33-,34+,35+,36-,37-,39-,40+,41+,42-/m0/s1 |
SMILES | O([H])[C@]1([H])C([H])([H])[C@]2([H])[C@@]3(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]([H])(C(C([H])([H])[H])(C([H])([H])[H])[C@]3([H])C([H])([H])C([H])([H])[C@@]2(C([H])([H])[H])[C@]2(C([H])([H])[H])C([H])([H])C([H])([H])[C@]([H])([C@](C([H])([H])[H])(C([H])([H])C([H])([H])/C(/[H])=C(\C([H])([H])[H])/C([H])([H])[H])O[C@@]3([H])[C@@]([H])([C@]([H])([C@@]([H])([C@@]([H])(C([H])([H])O[H])O3)O[H])O[H])O[H])[C@]21[H])O[C@@]1([H])[C@@]([H])([C@]([H])([C@@]([H])([C@@]([H])(C([H])([H])O[H])O1)O[H])O[H])O[H] |
LogP | 2.14900 |
PSA | 218.99000 |
沸点 | 871.488℃ at 760 mmHg |
颜色与性状 | Powder |
精确分子量 | 784.49700 |
氢键供体数量 | 9 |
氢键受体数量 | 13 |
可旋转化学键数量 | 10 |
同位素质量 | 784.49729235 g/mol |
重原子数量 | 55 |
复杂度 | 1370 |
同位素原子数量 | 0 |
确定原子立构中心数量 | 20 |
不确定原子立构中心数量 | 0 |
确定化学键立构中心数量 | 0 |
不确定化学键立构中心数量 | 0 |
共价键单元数量 | 1 |
疏水参数计算参考值(XlogP) | 4 |
拓扑分子极性表面积 | 219 |
分子量 | 785.0 |
1.
Synthesis of l-aspartic acid-based bimetallic hybrid nanoflowers to immobilize snailase for the production of rare ginsenoside compound K
Duoduo Tian,Zhansheng Wu,Xiaochen Liu,Zhuo Tu,Runze Li,Daidi Fan,Yiran Lan J. Mater. Chem. B 2023 11 2397
2.
A new approach for authentication of four ginseng herbs and their related products based on the simultaneous quantification of 19 ginseng saponins by UHPLC-TOF/MS coupled with OPLS-DA
Bao-ming Huang,Ting-bo Chen,Sheng-yuan Xiao,Qing-lin Zha,Pei Luo,Ying-ping Wang,Xiu-ming Cui,Liang Liu,Hua Zhou RSC Adv. 2017 7 46839
3.
Complete genome sequencing of Arachidicoccus ginsenosidimutans sp. nov., and its application for production of minor ginsenosides by finding a novel ginsenoside-transforming β-glucosidase
Muhammad Zubair Siddiqi,Siddiqi Muhammad Shafi,Wan-Taek Im RSC Adv. 2017 7 46745
4.
Protective effects of enhanced minor ginsenosides in Lactobacillus fermentum KP-3-fermented ginseng in mice fed a high fat diet
Bo Nan,Yan-long Liu,Ying You,Wan-cong Li,Jing-jing Fan,Yu-shan Wang,Chun-hong Piao,Dong-liang Hu,Gui-jiao Lu,Yu-hua Wang Food Funct. 2018 9 6020
5.
Highly efficient biotransformation of ginsenoside Rb1 and Rg3 using β-galactosidase from Aspergillus sp.
Hui-da Wan,Dan Li RSC Adv. 2015 5 78874
6.
Gut microbiota-mediated deglycosylation of ginsenoside Rb1 in rats: in vitro and in vivo insights from quantitative ultra-performance liquid chromatography-mass spectrometry analysis
Kang An,Zhang Shengjie,Shan Jinjun,Di Liuqing Anal. Methods 2015 7 6173
7.
Yiqi Fumai lyophilized injection attenuates doxorubicin-induced cardiotoxicity, hepatotoxicity and nephrotoxicity in rats by inhibition of oxidative stress, inflammation and apoptosis
Yue Gu,Aichun Ju,Bingjie Jiang,Jingze Zhang,Shuli Man,Changxiao Liu,Wenyuan Gao RSC Adv. 2018 8 40894
8.
Enzyme-modified Panax ginseng inhibits UVB-induced skin aging through the regulation of procollagen type I and MMP-1 expression
Eunson Hwang,Taek Hwan Lee,Sang-Yong Park,Tae Hoo Yi,Sun Yeou Kim Food Funct. 2014 5 265
9.
Individual and combined antioxidant effects of ginsenoside F2 and cyanidin-3-O-glucoside in human embryonic kidney 293 cells
Di Liu,Fengguang Pan,Jiyun Liu,Ying Wang,Ting Zhang,Erlei Wang,Jingbo Liu RSC Adv. 2016 6 81092
10.
Individual and combined use of ginsenoside F2 and cyanidin-3-O-glucoside attenuates H2O2-induced apoptosis in HEK-293 cells via the NF-κB pathway
Di Liu,Ying Wang,Shuang Ma,Hongyu Sun,Wenyan Shi,Xianmin Feng RSC Adv. 2017 7 41713
SMILES
CC(C)=CCC[C@@](O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1)(C)[C@@H]2[C@@H]3[C@](CC2)(C)[C@@]4(C)[C@H](C[C@H]3O)[C@]5(C)[C@@H](CC4)C(C)(C)[C@@H](O[C@H]6[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O6)CC5
物化性质
为白色粉末。
易溶于水、甲醇、乙醇,不溶于乙醚、苯。
来源
五加科植物人参Panax ginseng C. A. Mey.的干燥根。
药理作用
人参具有大补元气,滋补强壮,安神益智,生津,复脉固脱等功效。现代医学普遍认为人参对中 枢神经系统、心血管系统、消化系统、免疫系统、内分泌系统、泌尿生殖系统有广泛的作用,从而可提高人体力、智力的活动能力,增强机体对有害刺激的非特异性 抵抗力。人参的药理活性常因机体机能状态不同双向作用,因此人参是具有“适应原”样作用的典型代表药。