InChIKey | KURWKDDWCJELSV-UHFFFAOYSA-N |
Inchi | 1S/C16H12N2/c1-18-15-9-5-2-6-11(15)10-14-16(18)12-7-3-4-8-13(12)17-14/h2-10H,1H3 |
SMILES | N1(C)C2C=CC=CC=2C=C2C1=C1C=CC=CC1=N2 |
PSA | 15.6 |
溶解度 | DMSO: ≥5mg/mL |
精确分子量 | 232.10016 |
氢键供体数量 | 0 |
氢键受体数量 | 1 |
可旋转化学键数量 | 0 |
重原子数量 | 18 |
复杂度 | 316 |
同位素原子数量 | 0 |
确定原子立构中心数量 | 0 |
不确定原子立构中心数量 | 0 |
确定化学键立构中心数量 | 0 |
不确定化学键立构中心数量 | 0 |
共价键单元数量 | 1 |
疏水参数计算参考值(XlogP) | 3.3 |
互变异构体数量 | 无 |
表面电荷 | 0 |
拓扑分子极性表面积 | 17.8 |
EINECS | 9019 |
1.
Cryptolepine and quindoline: understanding their photophysics
Inês F. A. Mariz,Sandra Pinto,Jo?o Lavrado,Alexandra Paulo,José M. G. Martinho,Ermelinda M. S. Ma??as Phys. Chem. Chem. Phys. 2017 19 10255
2.
Recent synthetic efforts in the preparation of 2-(3,4)-alkenyl (aryl) quinoline molecules towards anti-kinetoplastid agents
Dayana Orozco,Vladimir V. Kouznetsov,Armando Bermúdez,Leonor Y. Vargas Méndez,Arturo René Mendoza Salgado,Carlos Mario Meléndez Gómez RSC Adv. 2020 10 4876
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Synthesis, analysis and biological evaluation of novel indolquinonecryptolepine analogues as potential anti-tumour agents
A. Le Gresley,V. Gudivaka,S. Carrington,A. Sinclair,J. E. Brown Org. Biomol. Chem. 2016 14 3069
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Fluorescent natural products as probes and tracers in biology
Romain Duval,Christophe Duplais Nat. Prod. Rep. 2017 34 161
5.
The uniqueness and therapeutic value of natural products from West African medicinal plants. Part I: uniqueness and chemotaxonomy
Fidele Ntie-Kang,Lydia L. Lifongo,Conrad V. Simoben,Smith B. Babiaka,Wolfgang Sippl,Luc Meva'a Mbaze RSC Adv. 2014 4 28728
6.
Imaging and therapeutic applications of Zn(ii)-cryptolepine–curcumin molecular probes in cell apoptosis detection and photodynamic therapy
Qi-Pin Qin,Zu-Zhuang Wei,Zhen-Feng Wang,Xiao-Ling Huang,Ming-Xiong Tan,Hua-Hong Zou,Hong Liang Chem. Commun. 2020 56 3999
7.
Recent developments in research on terrestrial plants used for the treatment of malaria
Colin W. Wright Nat. Prod. Rep. 2010 27 961
8.
Recent developments in research on terrestrial plants used for the treatment of malaria
Colin W. Wright Nat. Prod. Rep. 2010 27 961
9.
Microwave-assisted reductive cyclization: an easy entry to the indoloquinolines and spiro[2H-indole-2,3′-oxindole]
Prakash T. Parvatkar,Mahesh S. Majik RSC Adv. 2014 4 22481
10.
A concise Friedl?nder/Buchwald–Hartwig approach to the total synthesis of quindoline, a bioactive natural indoloquinoline alkaloid, and toward the unnatural 10-methylquindoline
María V. Méndez,Sebastian O. Simonetti,Teodoro S. Kaufman,Andrea B. J. Bracca New J. Chem. 2019 43 10803