| MDL | MFCD07636810 |
| InChIKey | GVKKJJOMQCNPGB-JTQLQIEISA-N |
| Inchi | 1S/C19H20O3/c1-10-9-22-18-12-6-7-13-11(5-4-8-19(13,2)3)15(12)17(21)16(20)14(10)18/h6-7,10H,4-5,8-9H2,1-3H3/t10-/m0/s1 |
| SMILES | O1C([H])([H])[C@]([H])(C([H])([H])[H])C2C(C(C3=C(C([H])=C([H])C4=C3C([H])([H])C([H])([H])C([H])([H])C4(C([H])([H])[H])C([H])([H])[H])C1=2)=O)=O |
| LogP | 3.44330 |
| PSA | 43.37000 |
| 折射率 | 1.602 |
| 沸点 | 459℃ at 760 mmHg |
| 熔点 | 192°C(lit.) |
| 闪点 | 203.4±28.8 °C |
| 溶解度 | DMSO: ≥5mg/mL |
| 颜色与性状 | Red cryst. |
| 敏感性 | 对光敏感 |
| 最大波长(λmax) | 263(lit.) |
| 光学活性 | [α]/D -85.0±3.0°, c = 0.1 in chloroform |
| 密度 | 1.2300 |
| 精确分子量 | 296.14100 |
| 氢键供体数量 | 0 |
| 氢键受体数量 | 3 |
| 可旋转化学键数量 | 0 |
| 同位素质量 | 296.14124450 g/mol |
| 重原子数量 | 22 |
| 复杂度 | 571 |
| 同位素原子数量 | 0 |
| 确定原子立构中心数量 | 1 |
| 不确定原子立构中心数量 | 0 |
| 确定化学键立构中心数量 | 0 |
| 不确定化学键立构中心数量 | 0 |
| 共价键单元数量 | 1 |
| 疏水参数计算参考值（XlogP） | 3.8 |
| 拓扑分子极性表面积 | 43.4 |
| 分子量 | 296.4 |
| 海关编码 | 2932999099 |
| 海关数据 |
中国海关编码：2932999099概述：2932999099. 其他仅含氧杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0% 申报要素：品名, 成分含量, 用途 Summary：2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
| 用途 | 具有抗氧化、抗衰老功能，对治疗冠心病、心绞痛、心肌损害有一定疗效。 |
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Cryptotanshinone inhibits proliferation and induces apoptosis via mitochondria-derived reactive oxygen species involving FOXO1 in estrogen receptor-negative breast cancer Bcap37 cells
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Screening target components from Radix salviae miltiorrhiae using an EGFR/CMC-online-HPLC/MS method
Sheng-Li Han,Tao Zhang,Jing Huang,Zhi-Gang Hu,Si-Cen Wang Anal. Methods 2012 4 1078
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Anticancer activity in human multiple myeloma U266 cells: synergy between cryptotanshinone and arsenic trioxide
Pei Liu,Shi Xu,Min Zhang,Wen Wen Wang,Yan Fang Zhang,Kanwal Rehman,Hua Naranmandura,Zhe Chen Metallomics 2013 5 871
4.
A novel hollow fiber/graphene oxide/solvent bar microextraction coupled with high performance liquid chromatography for preconcentration and determination of tanshinones and salvianolic acids in Radix Salvia miltiorrhiza
Wen-Yan Ma,Rong-Rong Xing,Shuang Hu,Xuan Chen,Xiao-Hong Bai Anal. Methods 2014 6 7285
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An in vitro affinity-based method for studying herb–drug interactions for direct identification of cytochrome P450 1A2, 3A4, and 2C9 specific ligands from herbal extracts using ultrafiltration-high performance liquid chromatography
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Recent advances in the discovery of protein tyrosine phosphatase SHP2 inhibitors
Jiao Kong,Ya-Qiu Long RSC Med. Chem. 2022 13 246
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An activity-calibrated chemical standardization approach for quality evaluation of Salvia miltiorrhiza Bge.
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Biosynthesis and absolute configuration of diterpene cryptotanshinone from Salvia miltiorrhiza: stereochemistry of methyl migration in the formation of the abietane skeleton determined by incorporation of D-[U-13C6]glucose
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Yizhou Dong,Susan L. Morris-Natschke,Kuo-Hsiung Lee Nat. Prod. Rep. 2011 28 529
| PubChemId | 354334480 |
| Reaxys RN | 5445400 |
| Beilstein | 5445400 |
物理化学性质
外观性状 橙色针状结晶(甲醇)
熔点 184℃～185℃
溶解性 溶于甲醇、乙醇、苯、乙醚，易溶于丙酮、氯仿。与浓硫酸作用显红色。在避光及非溶液状态下最稳定。
产品用途
隐丹参酮具有抑菌作用，1mg/ml对金黄色葡萄球菌及绿脓杆菌均有抑制作用，对溶血性链球菌亦有一定抑制作用。
应用领域
上下游产品信息
化学品安全说明书(MSDS)
储运特性
