16960-16-0_替可克肽CAS号:16960-16-0/替可克肽中英文名/分子式/结构式

替可克肽的其他展现形式

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简介

替可克肽是一种化学品，分子式 C136H210N40O31S

名称和标识符

InChIKey	ZOEFCCMDUURGSE-SQKVDDBVSA-N
Inchi	1S/C136H210N40O31S/c1-75(2)109(127(200)154-71-106(181)156-88(31-13-17-52-137)114(187)158-89(32-14-18-53-138)115(188)159-91(35-21-56-149-134(142)143)116(189)164-96(37-23-58-151-136(146)147)131(204)175-60-25-39-104(175)126(199)173-111(77(5)6)128(201)163-90(33-15-19-54-139)120(193)171-110(76(3)4)129(202)169-101(65-80-43-47-84(180)48-44-80)132(205)176-61-26-40-105(176)133(206)207)172-125(198)103-38-24-59-174(103)130(203)95(34-16-20-55-140)157-107(182)70-153-113(186)99(66-81-68-152-87-30-12-11-29-85(81)87)167-117(190)92(36-22-57-150-135(144)145)160-121(194)98(63-78-27-9-8-10-28-78)166-123(196)100(67-82-69-148-74-155-82)168-118(191)93(49-50-108(183)184)161-119(192)94(51-62-208-7)162-124(197)102(73-178)170-122(195)97(165-112(185)86(141)72-177)64-79-41-45-83(179)46-42-79/h8-12,27-30,41-48,68-69,74-77,86,88-105,109-111,152,177-180H,13-26,31-40,49-67,70-73,137-141H2,1-7H3,(H,148,155)(H,153,186)(H,154,200)(H,156,181)(H,157,182)(H,158,187)(H,159,188)(H,160,194)(H,161,192)(H,162,197)(H,163,201)(H,164,189)(H,165,185)(H,166,196)(H,167,190)(H,168,191)(H,169,202)(H,170,195)(H,171,193)(H,172,198)(H,173,199)(H,183,184)(H,206,207)(H4,142,143,149)(H4,144,145,150)(H4,146,147,151)/t86-,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,109-,110-,111-/m0/s1
SMILES	S(C([H])([H])[H])C([H])([H])C([H])([H])[C@@]([H])(C(N([H])[C@@]([H])(C([H])([H])C([H])([H])C(=O)O[H])C(N([H])[C@@]([H])(C([H])([H])C1=C([H])N([H])C([H])=N1)C(N([H])[C@@]([H])(C([H])([H])C1C([H])=C([H])C([H])=C([H])C=1[H])C(N([H])[C@@]([H])(C([H])([H])C([H])([H])C([H])([H])N([H])/C(=N/[H])/N([H])[H])C(N([H])[C@@]([H])(C([H])([H])C1=C([H])N([H])C2=C([H])C([H])=C([H])C([H])=C12)C(N([H])C([H])([H])C(N([H])[C@@]([H])(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C(N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(N([H])[C@]([H])(C(N([H])C([H])([H])C(N([H])[C@@]([H])(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C(N([H])[C@@]([H])(C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])C(N([H])[C@@]([H])(C([H])([H])C([H])([H])C([H])([H])N([H])/C(=N/[H])/N([H])[H])C(N([H])[C@@]([H])(C([H])([H])C([H])([H])C([H])([H])N([H])/C(=N/[H])/N([H])[H])C(N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(N([H])[C@]([H])(C(N([H])[C@]([H])(C(N([H])[C@]([H])(C(N([H])[C@@]([H])(C([H])([H])C1C([H])=C([H])C(=C([H])C=1[H])O[H])C(N1C([H])([H])C([H])([H])C([H])([H])[C@@]1([H])C(=O)O[H])=O)=O)C([H])(C([H])([H])[H])C([H])([H])[H])=O)C([H])([H])C([H])([H])C([H])([H])C([H])([H])N([H])[H])=O)C([H])(C([H])([H])[H])C([H])([H])[H])=O)=O)=O)=O)=O)=O)=O)C([H])(C([H])([H])[H])C([H])([H])[H])=O)=O)=O)=O)=O)=O)=O)=O)=O)N([H])C([C@]([H])(C([H])([H])O[H])N([H])C([C@]([H])(C([H])([H])C1C([H])=C([H])C(=C([H])C=1[H])O[H])N([H])C([C@]([H])(C([H])([H])O[H])N([H])[H])=O)=O)=O

别名信息

- 中文别名 -

替可克肽二十四肽促皮质素 BOC-L-天冬氨酸-4-叔丁酯促皮质24肽促肾上腺皮质激素片段 (1-24),人醋酸促肾上腺皮质激素 USP标准品醋酸替可克肽醋酸替可克肽 Tetracosactide Acetate 醋酸替可克肽 TetracosactideAcetate 人促肾上腺皮质激素(1-24),替可克肽人促肾上腺皮质激素(1-24)【ACTH】肾上腺皮质激素(人, 1-24)<电离质谱校准物> 替可沙肽替可沙肽 EP标准品克肽醋酸醋酸替可沙肽醋酸替可克肽 16960-16-0

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- 英文别名 -

Cosyntropin Adrenocorticotropic Hormone Fragment 1-24 human ACTH (1-24) (human, bovine, rat) ACTH (1-24), human ADRENOCORTICOTROPIC HORMONE FRAGMENT 1-24 Adrenocorticotropic Hormone Fragment 1-24 human, rat Adrenocorticotropic Hormone, Human (1-24) Cosyntropin（1mg） Tetracosactide Acetate Tetracosactrin α1-24-Adrenocorticotropic Hormone α1-24-Adrenocorticotropic-d4 Hormone H-SYSMEHFRWGKPVGKKRRPVKVYP-OH (1-24)a-ACTH 1-24 ACTH (human) 1-24corticotropin (human) 8: PN: WO0069900 SEQID: 7 unclaimedsequence ACTH1-24 ACTHa1-24 Actholain Adrenocorticotropin(1-24) Ba 30920 Ba 36716 Corticotropin-(1-24) Cortrophin S Cortrosinta Cortrosyn HumanACTH (1-24) L-Proline, L-seryl-L-tyrosyl-L-seryl-L-methionyl-L-glutamyl-L-a-histidyl-L-phenylalanyl-L-arginyl-L-tryptophylglycyl-L-lysyl-L-prolyl-L-valylglycyl-L-lysyl-L-lysyl-L-arginyl-L-arginyl-L-prolyl-L-valyl-L-lysyl-L-valyl-L-tyrosyl- Nuvacthen Depot PN: WO9952928 SEQID: 9 claimed protein Porcine ACTH (1-24) Synacthen Synacthene Synacthene-retard Synecthen Tetracosactid Tetracosactide Tetracosapeptide a1-24-ACTH a1-24-Adrenocorticotropic hormone b-Corticotrophin-(1-24)-tetracosapeptide b1-24-ACTH b1-24-Corticotropin b1-24-Tetracosactide acth-z C06926 α1-24-ACTH 10: PN: WO03051390 PAGE: 52 claimed protein 20: PN:WO2006052468 SEQID: 2 claimed sequence 2136: PN: WO03060071 SEQID: 2198unclaimed 4: PN: WO2004045592 SEQID: 3 unclaimed sequence 7: PN:US20090175821 SEQID: 7 claimed protein ba30920 ba36716 VICOTROPE CORTICOTROPIN TETRACOSAPEPTIDE BDBM50017180 U943 960S160 L-Seryl-L-tyrosyl-L-seryl-L-methionyl-L-glutamyl-L-alpha-histidyl-L-phenylalanyl-L-arginyl-L-tryptophylglycyl-L-lysyl-L-prolyl-L-valylglycyl-L-lysyl-L-lysyl-L-arginyl-L-arginyl-L-prolyl-L-

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物化性质

计算特性

精确分子量	2931.58000
氢键供体数量	42
氢键受体数量	41
可旋转化学键数量	96
重原子数量	208
复杂度	6500
同位素原子数量	0
确定原子立构中心数量	21
不确定原子立构中心数量	1
确定化学键立构中心数量	0
不确定化学键立构中心数量	0
共价键单元数量	1
疏水参数计算参考值（XlogP）	-7.9
互变异构体数量	1000
表面电荷	0
拓扑分子极性表面积	1180

实验特性

LogP	6.74150
PSA	1184.02000
水溶性	Soluble in water
颜色与性状	白色或淡黄色粉末
溶解性	极易溶于水，水溶液不稳定。

安全信息纠错

RTECS号	GM7915000
WGK Germany	3
储存条件	Powder -80°C 2 years -20°C 1 year In solvent -80°C 6 months -20°C 1 month

参考资料

Beilstein

241-031-1

替可克肽 | 16960-16-0